Scientific Posters

Validated Multi-site GLP-compliant Analysis of Solithromycin (SOLI) in Monkey Plasma Samples Following Filtration to Remove Potentially Active Anthrax Spores
8th Workshop on Recent Issues in Bioanalysis (WRIB) - March 2014
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Case Studies

Optimizing enzymatic digestion to create a stable derivative enabled us to develop an LC/MS/MS method to measure concentrations of a key biomarker directly related to the activity of a biologic.
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The development of a novel extraction and derivatization scheme to simultaneously determine free and covalently bound drug concentrations using a single assay.
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The development of a non-traditional internal standard by derivatization allowed our client to maintain their rigorous timeline without resorting to an expensive synthetic effort.
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Employing selective extraction in method development enabled the accurate determination of in vivo drug concentration in plasma samples collected during our client’s Phase I trial.
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Customizing specimen collection kits for specific clinical trial sampling requirements streamlined our client’s Phase I study and helped ensure that all specimens collected were stabilized, properly labeled, and provided accurate pharmacokinetic data.
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Increasing assay sensitivity to determine drug concentration in epithelial lining fluid (ELF) samples allowed our client’s clinical trial to proceed uninterrupted, saving them time and resources.
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